Acetaldehyde → HCID 57825650, compound

HRID 2281953Notes

Reaction equation

HRID 2281953 reaction equation
[OH:1][C@@H:2]1[CH2:6][CH2:5][NH:4][CH2:3]1.N[CH2:8][C@@H:9]1CC[CH2:11][N:10]1CC.C(=O)C>>[CH3:11][NH:10][CH2:9][CH2:8][N:4]1[CH2:5][CH2:6][C@@H:2]([OH:1])[CH2:3]1

Participants

4

Reactant 3

HCID 177AcetaldehydeHCID 643457(S)-(-)-2-Aminomethyl-1-ethylpyrrolidineHCID 2759337(R)-3-Pyrrolidinol

Product 1

HCID 57825650HCID 57825650, compound

Procedure

By using (R)-3-hydroxypyrrolidine (2.0 g) as a starting material, the title compound (210 mg) was obtained in the same manners as those of Reference Example 1, (1) and Reference Example 19, (3).

Sources & evidence

ORD record
ord-117ea6b8567042c6a3b27e636c4432d8
Source dataset
uspto-grants-2015_09
Patent number
US09139609B2

Reaction notes

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