Acetaldehyde → HCID 89964489, compound

HRID 2281955Notes

Reaction equation

HRID 2281955 reaction equation
[CH3:1][N:2]([CH3:8])[C@@H:3]1[CH2:7][CH2:6][NH:5][CH2:4]1.N[CH2:10][C@@H:11]1CC[CH2:13][N:12]1CC.C(=O)C>>[CH3:1][N:2]([CH3:8])[C@@H:3]1[CH2:7][CH2:6][N:5]([CH2:10][CH2:11][NH:12][CH3:13])[CH2:4]1

Participants

4

Reactant 3

HCID 177AcetaldehydeHCID 643457(S)-(-)-2-Aminomethyl-1-ethylpyrrolidineHCID 2758521(3R)-(+)-3-(Dimethylamino)pyrrolidine

Product 1

HCID 89964489HCID 89964489, compound

Procedure

By using (3R)-(+)-3-(dimethylamino)pyrrolidine (200 mg) as a starting material, the title compound (123 mg) was obtained in the same manners as those of Reference Example 1, (1) and Reference Example 19, (3).

Sources & evidence

ORD record
ord-99d4d654b4e44a54bd5e8966b33eda68
Source dataset
uspto-grants-2015_09
Patent number
US09139609B2

Reaction notes

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