Acetaldehyde → HCID 68282342, compound

HRID 2281956Notes

Reaction equation

HRID 2281956 reaction equation
[CH3:1][N:2]([CH3:8])[C@H:3]1[CH2:7][CH2:6][NH:5][CH2:4]1.N[CH2:10][C@@H:11]1CC[CH2:13][N:12]1CC.C(=O)C>>[CH3:1][N:2]([CH3:8])[C@H:3]1[CH2:7][CH2:6][N:5]([CH2:10][CH2:11][NH:12][CH3:13])[CH2:4]1

Participants

4

Reactant 3

HCID 177AcetaldehydeHCID 643457(S)-(-)-2-Aminomethyl-1-ethylpyrrolidineHCID 7019156(3S)-(-)-3-(Dimethylamino)pyrrolidine

Product 1

HCID 68282342HCID 68282342, compound

Procedure

By using (3S)-(−)-3-(dimethylamino)pyrrolidine (200 mg) as a starting material, the title compound (80 mg) was obtained in the same manners as those of Reference Example 1, (1) and Reference Example 19, (3).

Sources & evidence

ORD record
ord-d0e7be1a829b4fd1a3c6342535d49cff
Source dataset
uspto-grants-2015_09
Patent number
US09139609B2

Reaction notes

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