Acetaldehyde → HCID 28824001, compound

HRID 2281966Notes

Reaction equation

[CH3:1][N:2]1[CH2:8][C:6](=[O:7])[NH:5][C:3]1=[O:4].[NH2:9][CH2:10][C@@H:11]1[CH2:15][CH2:14]CN1CC.C(=O)C>>[NH2:9][CH2:10][CH2:11][CH2:15][CH2:14][N:5]1[C:6](=[O:7])[CH2:8][N:2]([CH3:1])[C:3]1=[O:4]

Participants

Reactant 3

HCID 177Acetaldehyde

HCID 692171-Methylhydantoin

HCID 643457(S)-(-)-2-Aminomethyl-1-ethylpyrrolidine

Product 1

HCID 28824001HCID 28824001, compound

Procedure

By using 1-methylhydantoin (2.8 g) as a starting material, the title compound (1.38 g) was obtained in the same manners as those of Reference Example 63, (1) and Reference Example 9, (2).

Sources & evidence

ORD record: ord-b7dc4b322cde4cceb74f86c114ec97f0
Source dataset: uspto-grants-2015_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09139609B2

Reaction notes

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