Dimethylamine → HCID 89964232, compound

HRID 2281975Notes

Reaction equation

HRID 2281975 reaction equation
C(O[C:6]([NH:8][C@H:9]([C:19]([OH:21])=O)[CH2:10]OCC1C=CC=CC=1)=O)(C)(C)C.[CH3:22][NH:23][CH3:24]>>[CH3:22][N:23]([CH3:24])[CH2:10][C@@H:9]([NH:8][CH3:6])[CH2:19][OH:21]

Participants

3

Reactant 2

HCID 674DimethylamineHCID 90234L-Serine, N-[(1,1-dimethylethoxy)carbonyl]-O-(phenylmethyl)-

Product 1

HCID 89964232HCID 89964232, compound

Procedure

By using N-(t-butoxycarbonyl)-O-benzyl-(L)-serine (2.50 g) and 50% aqueous dimethylamine (3 ml) as starting materials, the title compound (0.58 g) was obtained in the same manners as those of Reference Example 34, (1), Reference Example 107, (2) and Reference Example 7, (2).

Sources & evidence

ORD record
ord-e663dfe4b4c84ba980a0fe32ceee960a
Source dataset
uspto-grants-2015_09
Patent number
US09139609B2

Reaction notes

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