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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2282103Generated: October 30, 2026

4-Hydroxyphenylpyruvic Acid → 8-benzyl-2-[(4-hydroxyphenyl)methyl]-6-phenyl-7H-imidazo[1,2-a]pyrazin-3-one

https://huagongshe.com/reaction/2282103

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Hydroxyphenylpyruvic AcidHCID 979—
Reactant2-Amino-3-benzyl-5-phenylpyrazineHCID 10214659—
Product8-benzyl-2-[(4-hydroxyphenyl)methyl]-6-phenyl-7H-imidazo[1,2-a]pyrazin-3-oneHCID 178515648—

Reaction Steps

Synthesized using method A with 3-(4-hydroxyphenyl)-2-oxopropanoic acid and 3-benzyl-5-phenylpyrazin-2-amine as starting materials. Exact mass calculated for C26H22N3O2+ m/z+408.17, found m/z+408.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09139836B2
Source datasetuspto-grants-2015_09
ORD IDord-f5b462aa001d4ff0b57718aa2947ea78
Source noteuspto-grants-2015_09