p-Toluenesulfonic acid monohydrate → HCID 178427649, compound

Participants

Reaction Steps

To a suspension of 2-methyl-5-(3-morpholin-4-ylpropoxy)-3-[4-phenyl-5-(1H-1,2,4-triazol-3-yl)-1,3-thiazol-2-yl]pyrazolo[1,5-a]pyridine (85.8 mg, 0.171 mmol) obtained above in EtOH (10 mL), was added a solution of p-toluene sulfonic acid monohydrate (71.6 mg, 0.376 mmol) in EtOH (2 mL) and then resulting mixture was concentrated under reduced pressure. The residue was crystallized from EtOH (2 mL) and EtOAc (6 mL) to obtain title compound (106 mg, 92%) as a pale yellow solid.

Provenance & Evidence