p-Toluenesulfonic acid monohydrate → HCID 178427643, compound

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Reaction Steps

The title compound has been prepared according to the similar manner described in 85-B (iv) from 5-[2-(4-fluoropiperidin-1-yl)ethoxy]-2-methyl-3-[4-phenyl-5-(1H-1,2,4-triazol-3-yl)-1,3-thiazol-2-yl]pyrazolo[1,5-a]pyridine (89.3 mg, 0.177 mmol) and p-toluenesulfonic acid monohydrate (74.1 mg, 0.389 mmol). The crude product was crystallized from EtOH (1 mL) and EtOAc (4 mL) to give pure title compound (137 mg, 91%) as a yellow solid.

Provenance & Evidence