p-Toluenesulfonic acid monohydrate → HCID 178427645, compound

Participants

Reaction Steps

The title compound has been prepared according to the similar manner described in 85-B (iv) from 2-methyl-5-[2-(4-methylpiperazin-1-yl)ethoxy]-3-[4-phenyl-5-(1H-1,2,4-triazol-3-yl)-1,3-thiazol-2-yl]pyrazolo[1,5-a]pyridine (32.5 mg, 0.0649 mmol) and p-toluenesulfonic acid monohydrate (27.2 mg, 0.143 mmol). Title compound (48 mg, 87%) has been obtained as a yellow solid by the addition of EtOAc to the reaction mixture followed by collection of the resulting precipitate by filtration.

Provenance & Evidence