HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 178427646, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | p-Toluenesulfonic acid monohydrate | HCID 521998 | — |
| Reactant | HCID 178433762 | HCID 178433762 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 178427646 | HCID 178427646 | 85% |
Reaction Steps
The title compound has been prepared according to the similar manner described in 85-B (iv) from 2-methyl-5-{2-[4-(methylsulfonyl)piperazin-1-yl]ethoxy}-3-[4-phenyl-5-(1H-1,2,4-triazol-3-yl)-1,3-thiazol-2-yl]pyrazolo[1,5-a]pyridine (45.3 mg, 0.0802 mmol) and p-toluenesulfonic acid monohydrate (33.6 mg, 0.176 mmol). The pure title compound (62 mg, 85%) has been obtained as a yellow solid by crystallization from EtOH (1 mL) and EtOAc (3 mL).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09139589B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-da9a17cec0d341eea0d744f17aa37de0 |
| Source note | uspto-grants-2015_09 |