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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2282241Generated: October 30, 2026

Ethanol → HCID 178427646, compound

https://huagongshe.com/reaction/2282241

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
Reactantp-Toluenesulfonic acid monohydrateHCID 521998—
ReactantHCID 178433762HCID 178433762—
SolventEthyl AcetateHCID 8857—
ProductHCID 178427646HCID 17842764685%

Reaction Steps

The title compound has been prepared according to the similar manner described in 85-B (iv) from 2-methyl-5-{2-[4-(methylsulfonyl)piperazin-1-yl]ethoxy}-3-[4-phenyl-5-(1H-1,2,4-triazol-3-yl)-1,3-thiazol-2-yl]pyrazolo[1,5-a]pyridine (45.3 mg, 0.0802 mmol) and p-toluenesulfonic acid monohydrate (33.6 mg, 0.176 mmol). The pure title compound (62 mg, 85%) has been obtained as a yellow solid by crystallization from EtOH (1 mL) and EtOAc (3 mL).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09139589B2
Source datasetuspto-grants-2015_09
ORD IDord-da9a17cec0d341eea0d744f17aa37de0
Source noteuspto-grants-2015_09