59177-46-7 → Benzamide

HRID 2282781Notes

Reaction equation

HRID 2282781 reaction equation
[H][H].S[C:4]1[CH:12]=[CH:11][C:7]([C:8]([NH2:10])=[O:9])=[CH:6][CH:5]=1>CO.[Au]>[C:8]([NH2:10])(=[O:9])[C:7]1[CH:11]=[CH:12][CH:4]=[CH:5][CH:6]=1

Participants

5

Reactant 2

HCID 2235161259177-46-7HCID 178418361HCID 178418361, compound

Product 1

HCID 2331Benzamide

Reagents, catalysts & solvents 2

HCID 23985GoldCatalystHCID 887MethanolSolvent

Procedure

Gold substrates were annealed in a hydrogen flame to get rid of contamination and form well ordered Au surfaces. 4-Mercaptobenzamide prepared according to Example 4 was dissolved (1 mM) in methanol and degassed using argon to avoid oxidation of thiols. The insulated tips treated substrates were immersed in this solution for >2 hours. This resulted in the formation of monolayers of benzamide on the surface. Extended functionalization times degraded insulation on the probes so treatment of probes was limited to 2 h. Functionalization of gold substrates was carried out for up to 20 hours.

Workup

  1. temperatureflame
  2. customto get rid of contamination
  3. customform well ordered Au surfaces
  4. customdegassed
  5. additionThe insulated tips treated substrates
  6. waitwere immersed in this solution for >2 hours

Sources & evidence

ORD record
ord-9806d765b84c46838e689ae673bf153b
Source dataset
uspto-grants-2015_09
Patent number
US09140682B2

Reaction notes

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