HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenacyl bromide → HCID 86614157, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenacyl bromide | HCID 6259 | — |
| Reactant | 1-Azabicyclo[2.2.2]oct-4-yl(diphenyl)methanol | HCID 23992385 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 86614157 | HCID 86614157 | 43.1% |
Reaction Steps
Following the general procedure outlined in Example 4, 1-azabicyclo[2.2.2]oct-4-yl(diphenyl)methanol (0.0567 g, 0.193 mmol) and 2-bromo-1-phenylethanone (0.0487 g, 0.245 mmol) in 2 CH3CN/3 CHCl3 (2.5 mL) were reacted to give the desired product (0.0410 g, 43.0%). EI-MS m/z 412 (M+) Rt (1.90 min).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09144571B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-2ac3ef9103e6461e8f47fc5c1220fdd6 |
| Source note | uspto-grants-2015_09 |