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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2283097Generated: October 31, 2026

1-(3-Bromopropoxy)-4-fluorobenzene → HCID 11548210, compound

https://huagongshe.com/reaction/2283097

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-Bromopropoxy)-4-fluorobenzeneHCID 260004—
Reactant1-Azabicyclo[2.2.2]oct-4-yl(diphenyl)methanolHCID 23992385—
SolventAcetonitrileHCID 6342—
ProductHCID 11548210HCID 1154821043.7%

Reaction Steps

Following the general procedure outlined in Example 3, 1-azabicyclo[2.2.2]oct-4-yl(diphenyl)methanol (0.0182 g, 0.0621 mmol) and 3-bromopropyl 4-fluorophenyl ether (0.0173 g, 0.0742 mmol) in 2 CH3CN/3 CHCl3 (4.0 mL) were reacted to give the desired product (0.0143 g, 43.7%). EI-MS m/z 446 (M+) Rt (1.96 min).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09144571B2
Source datasetuspto-grants-2015_09
ORD IDord-863eac109bbe4a5a922e891362006ce8
Source noteuspto-grants-2015_09