HCID 42645534, compound → HCID 42645532, compound

Participants

Reaction Steps

2-[[(E)-1-(4-Chlorophenyl)prop-1-en-2-yl]sulfonylamino]benzenesulfonamide (100 mg, 0.26 mmol) was dissolved in ethyl acetate (3 ml) and subjected to the H-cube (1 ml/min, full hydrogen. 10% Pd/C, 3 runs). The material obtained was purified by preparative HPLC (XTerra MS C8 column, acetonitrile/ammonium acetate buffer) to give the title compound (38 mg, 38%). The compound of Example 8 was also obtained.

Provenance & Evidence