HCID 42644369, compound → HCID 42644133, compound

Participants

Reaction Steps

A mixture of 2-[[(E)-2-(4-chlorophenyl)prop-1-enyl]sulfonylamino]benzenesulfonamide and 2-[2-(4-chlorophenyl)prop-2-enylsulfonylamino]benzenesulfonamide (40 mg, 0.11 mmol) was dissolved in methanol (3 ml) and subjected to the H-cube (1 ml/min, full hydrogen. 10% Pd/C, 2 runs). The product obtained was purified by preparative HPLC (XTerra MS C8 column, acetonitrile/ammonium acetate buffer) to give the title compound (13 mg, 32%) as a white solid.

Provenance & Evidence