HCID 42644369, compound → HCID 57751047, compound

Participants

Reaction Steps

A mixture of (E)-2-(2-(4-chlorophenyl)prop-1-enylsulfonamido)benzenesulfonamide and 2-[2-(4-chlorophenyl)prop-2-enylsulfonylamino]benzenesulfonamide (100 mg, 0.26 mmol) was dissolved in EtOAc in a 5 mL syringe. The solution was filtered and injected into the H-cube (1 ml/min, full hydrogen. 10% Pd/C). The solvent was then removed under reduced pressure and the crude material was purified by preparative HPLC (XTerra MS C8 column, acetonitrile/ammonium acetate buffer) to give the title compound (56 mg, 56%).

Provenance & Evidence