Ethanol → HCID 68782330, compound

Participants

Reaction Steps

A solution of 4-(2,3-dichloro-benzenesulfonylamino)-3-sulfamoyl-benzoic acid (1.3 g, 3.05 mmol) in ethanol (20 mL) was stirred at RT and a few drops of thionyl chloride were added. The reaction mixture was heated at reflux for 7 h, cooled to RT and concentrated under reduced pressure. The residue was purified by flash column chromatography using ethyl acetate/hexane (1:1) as eluent to afford the title compound (1.4 g, 100%).

Provenance & Evidence