2-Aminobenzenesulfonamide → HCID 57750947, compound

HRID 2283332Notes

Reaction equation

HRID 2283332 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8]([NH2:11])(=[O:10])=[O:9].[F:12][C:13]([F:27])([F:26])[C:14]1[CH:15]=[C:16](/[CH:20]=[CH:21]/[S:22](Cl)(=[O:24])=[O:23])[CH:17]=[CH:18][CH:19]=1>>[F:27][C:13]([F:12])([F:26])[C:14]1[CH:15]=[C:16](/[CH:20]=[CH:21]/[S:22]([NH:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[S:8]([NH2:11])(=[O:9])=[O:10])(=[O:23])=[O:24])[CH:17]=[CH:18][CH:19]=1

Participants

3

Reactant 2

HCID 728942-AminobenzenesulfonamideHCID 57750915HCID 57750915, compound

Product 1

HCID 57750947HCID 57750947, compoundYield 37%

Procedure

The title compound was synthesized as described for Example 178 in 37% yield, starting from 2-aminobenzenesulfonamide and (E)-2-(3-(trifluoromethyl)phenyl)ethenesulfonyl chloride.

Sources & evidence

ORD record
ord-7115905263d245999841b5e028ec4679
Source dataset
uspto-grants-2015_09
Patent number
US09145380B2

Reaction notes

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