2-Aminobenzenesulfonamide → HCID 57751028, compound

HRID 2283333Notes

Reaction equation

HRID 2283333 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8]([NH2:11])(=[O:10])=[O:9].[F:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1/[CH:19]=[CH:20]/[S:21](Cl)(=[O:23])=[O:22]>>[F:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1/[CH:19]=[CH:20]/[S:21]([NH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8]([NH2:11])(=[O:9])=[O:10])(=[O:23])=[O:22]

Participants

3

Reactant 2

HCID 728942-AminobenzenesulfonamideHCID 23469663HCID 23469663, compound

Product 1

HCID 57751028HCID 57751028, compoundYield 31%

Procedure

The title compound was synthesized as described for Example 178 in 31% yield, starting from 2-aminobenzenesulfonamide and (E)-2-(2-fluorophenyl)ethenesulfonyl chloride.

Sources & evidence

ORD record
ord-a8af077054a04390bf1c7093a75b9e94
Source dataset
uspto-grants-2015_09
Patent number
US09145380B2

Reaction notes

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