反应详情

A solution of 2-amino-5-chlorobenzenesulfonamide (0.041 g, 0.20 mmol) and (E)-2-(4-chloro-2-methoxyphenyl)ethenesulfonyl chloride (0.053 g, 0.20 mmol) in pyridine (2 mL) was stirred at room temperature over night. The reaction mixture was concentrated, 1 M hydrochloric acid was added and the mixture was extracted with dichloromethane. The organic phase was dried over magnesium sulfate and the solvent was evaporated to give 0.087 g (99% yield) of the title compound.

1. concentrationThe reaction mixture was concentrated
2. addition1 M hydrochloric acid was added
3. extractionthe mixture was extracted with dichloromethane
4. dry with materialThe organic phase was dried over magnesium sulfate
5. customthe solvent was evaporated