HuagongsheHuagongshe Chemistry Print Report · For research reference only
(E)-2-(3,4-dichlorophenyl)ethenesulfonyl chloride → (E)-2-(2-(3,4-Dichlorophenyl)vinylsulfonamido)-4,6-difluorobenzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (E)-2-(3,4-dichlorophenyl)ethenesulfonyl chloride | HCID 22719686 | — |
| Reactant | 2-Amino-4,6-difluorobenzenesulfonamide | HCID 23104229 | — |
| Product | (E)-2-(2-(3,4-Dichlorophenyl)vinylsulfonamido)-4,6-difluorobenzenesulfonamide | HCID 57751001 | 49% |
Reaction Steps
The title compound was synthesized as described for Example 194 a) in 49% yield, starting from 2-amino-4,6-difluorobenzenesulfonamide and (E)-2-(3,4-dichlorophenyl)ethenesulfonyl chloride (1.5 equiv.). Purification by column chromatography, using chloroform/methanol (95:5) as the eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09145380B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-d48d2c8f5ed1437cb381649be600fe7e |
| Source note | uspto-grants-2015_09 |