HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-chlorobenzenesulphonamide → (E)-5-Chloro-2-(2-(3,4-dichlorophenyl)vinylsulfonamido)benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-chlorobenzenesulphonamide | HCID 12295550 | — |
| Reactant | (E)-2-(3,4-dichlorophenyl)ethenesulfonyl chloride | HCID 22719686 | — |
| Product | (E)-5-Chloro-2-(2-(3,4-dichlorophenyl)vinylsulfonamido)benzenesulfonamide | HCID 57751005 | 49% |
Reaction Steps
The title compound was synthesized as described for Example 194 a) in 49% yield, starting from 2-amino-5-chlorobenzenesulfonamide and (E)-2-(3,4-dichlorophenyl)ethenesulfonyl chloride (1.5 equiv.). Purification by column chromatography, using chloroform/methanol (95:5) as the eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09145380B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-5cb6d5218fc24860b04635958a6b4664 |
| Source note | uspto-grants-2015_09 |