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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2283359Generated: November 1, 2026

Cyclopentylacetylene → 2-[2-(4-Cyclopentylethynyl-phenyl)-ethanesulfonylamino]-5-hydroxymethyl-benzenesulfonamide

https://huagongshe.com/reaction/2283359

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopentylacetyleneHCID 136725—
Reactant2-[2-(4-Bromo-phenyl)-ethanesulfonylamino]-5-hydroxymethyl-benzenesulfonamideHCID 57751051—
Product2-[2-(4-Cyclopentylethynyl-phenyl)-ethanesulfonylamino]-5-hydroxymethyl-benzenesulfonamideHCID 5775094611%

Reaction Steps

The title compound was synthesized as described for Example 210 in 11% yield, starting from 2-[2-(4-bromo-phenyl)-ethanesulfonylamino]-5-hydroxymethyl-benzenesulfonamide and ethynyl-cyclopentane. Purification by preparative HPLC.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09145380B2
Source datasetuspto-grants-2015_09
ORD IDord-c6bff90eb2df4c2a87d1307703a3c935
Source noteuspto-grants-2015_09