2-Amino-4-chlorobenzenesulphonamide → (E)-4-Chloro-2-(2-(4-chloro-2-methoxyphenyl)vinylsulfonamido)benzenesulfonamide

HRID 2283373Notes

Reaction equation

HRID 2283373 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[S:9]([NH2:12])(=[O:11])=[O:10].[Cl:13][C:14]1[CH:19]=[CH:18][C:17](/[CH:20]=[CH:21]/[S:22](Cl)(=[O:24])=[O:23])=[C:16]([O:26][CH3:27])[CH:15]=1>>[Cl:8][C:6]1[CH:5]=[CH:4][C:3]([S:9]([NH2:12])(=[O:11])=[O:10])=[C:2]([NH:1][S:22](/[CH:21]=[CH:20]/[C:17]2[CH:18]=[CH:19][C:14]([Cl:13])=[CH:15][C:16]=2[O:26][CH3:27])(=[O:23])=[O:24])[CH:7]=1

Participants

3

Reactant 2

HCID 777902-Amino-4-chlorobenzenesulphonamideHCID 22711054(E)-2-(4-chloro-2-methoxyphenyl)ethenesulfonyl chloride

Product 1

HCID 57750992(E)-4-Chloro-2-(2-(4-chloro-2-methoxyphenyl)vinylsulfonamido)benzenesulfonamideYield 100%

Procedure

The title compound was synthesized as described for Example 226 a) in 100% yield, starting from 2-amino-4-chlorobenzenesulfonamide and (E)-2-(4-chloro-2-methoxyphenyl)ethenesulfonyl chloride.

Sources & evidence

ORD record
ord-4810bf14cc1c44629d34fe28bd64ea66
Source dataset
uspto-grants-2015_09
Patent number
US09145380B2

Reaction notes

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