Hydrochloric Acid → HCID 117875143, compound

Participants

Reaction Steps

Step 4 A mixture of {2-[(S)-3-(3-benzoyl-4-chloro-2-fluoro-benzylamino)-butyrylamino]-ethyl}-carbamic acid tert-butyl ester (92 mg) and 2N hydrogen chloride in ethyl acetate (2 ml) was allowed to stand at room temperature for 60 minutes. The mixture was concentrated and re-concentrated from methanol (×2). Ethyl acetate was added to the residue and a solid produced by scratching. The material was obtained by filtration and was dried in a vacuum oven furnishing the desired compound as a white solid (56.1 mg).

Provenance & Evidence