Hydrogen chloride-ethyl acetate → HCID 89544649, compound

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Reaction Steps

3-{(S)-1-[4-Chloro-2-fluoro-3-(pyridine-3-carbonyl)-phenyl]-propylcarbamoyl}-2,5-dihydro-pyrrole-1-carboxylic acid tert-butyl ester (0.125 g, 0.26 mmol) treated with saturated HCl/EtOAc stirred at ambient for 1 hour, solid filtered off then purified by Prep HPLC to give N-[(1S)-1-{4-chloro-2-fluoro-3-[(pyridin-3-yl)carbonyl]phenyl}propyl]-2,5-dihydro-1H-pyrrole-3-carboxamide (0.062 g), MS: [M+H] 388

Provenance & Evidence