Methyl iodide → HCID 53796804, compound

HRID 2283683Notes

Reaction equation

HRID 2283683 reaction equation
[CH3:1][C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[CH:7][NH:8]2)=[C:4]([N+:11]([O-])=O)[CH:3]=1.[CH3:14]I>>[CH3:14][N:8]1[C:9]2[CH:10]=[C:2]([CH3:1])[CH:3]=[C:4]([NH2:11])[C:5]=2[CH:6]=[CH:7]1

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 247287646-Methyl-4-nitro-1H-indole

Product 1

HCID 53796804HCID 53796804, compound

Procedure

In accordance with Example 9 (Steps 1 and 2), 6-methyl-4-nitro-1H-indole was used instead of 4-nitro-1H-indole, and methyl iodide was used instead of ethyl bromide-d5 to obtain 1,6-dimethyl-1H-indol-4-amine.

Sources & evidence

ORD record
ord-233987e09cc0434f99f4503de98f79fd
Source dataset
uspto-grants-2015_09
Patent number
US09145414B2

Reaction notes

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