Methyl iodide → HCID 59276543, compound

HRID 2283709Notes

Reaction equation

HRID 2283709 reaction equation
[CH3:1][C:2]1[CH:10]=[C:9]([N+:11]([O-])=O)[CH:8]=[C:7]2[C:3]=1[CH:4]=[N:5][NH:6]2.I[CH3:15]>>[CH3:15][N:6]1[C:7]2[C:3](=[C:2]([CH3:1])[CH:10]=[C:9]([NH2:11])[CH:8]=2)[CH:4]=[N:5]1.[CH3:15][N:5]1[CH:4]=[C:3]2[C:7]([CH:8]=[C:9]([NH2:11])[CH:10]=[C:2]2[CH3:1])=[N:6]1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 24728762HCID 24728762, compound

Product 2

HCID 59276543HCID 59276543, compoundHCID 90308889HCID 90308889, compound

Procedure

In accordance with Example 24 (Steps 1 and 2), 4-methyl-6-nitro-1H-indazole was used instead of 6-nitro-1H-indazole, and iodomethane was used instead of sodium chlorodifluoroacetate to obtain 1,4-dimethyl-1H-indazol-6-amine and 2,4-dimethyl-2H-indazol-6-amine.

Sources & evidence

ORD record
ord-ade499f1818f47c89b8c68e9faf42eb7
Source dataset
uspto-grants-2015_09
Patent number
US09145414B2

Reaction notes

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