HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 5-ethyl-1-methyl-1H-pyrazole-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 5-ethyl-1-methyl-1H-pyrazole-3-carboxamide | HCID 66958582 | — |
| Product | 5-ethyl-1-methyl-1H-pyrazole-3-carbonitrile | HCID 66958843 | 79.3% |
Reaction Steps
5-Ethyl-1-methyl-1H-pyrazole-3-carboxamide (3.8 g, 25 mmol) was treated with phosphorous oxychloride (18 mL, 0.19 mol) according to the method described in Part C of Example 8 to provide 2.68 g of 5-ethyl-1-methyl-1H-pyrazole-3-carbonitrile as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09145410B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-2cfa7c89cd3d4cbab1825afbd52c9bf0 |
| Source note | uspto-grants-2015_09 |