HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus oxychloride → 1,5-diethyl-1H-pyrazole-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 1,5-diethyl-1H-pyrazole-3-carboxamide | HCID 66958535 | — |
| Product | 1,5-diethyl-1H-pyrazole-3-carbonitrile | HCID 66958300 | 101.9% |
Reaction Steps
1,5-Diethyl-1H-pyrazole-3-carboxamide (8.3 g, 0.050 mol) was treated with phosphorous oxychloride (35 mL) according to the method described in Part C of Example 7. The reaction was heated for 2.5 hours to provide 7.6 g of 1,5-diethyl-1H-pyrazole-3-carbonitrile as a yellow oil, which was used without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09145410B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-3fe8159fd0af4a5aae9905aaad922811 |
| Source note | uspto-grants-2015_09 |