HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluoropyridine-5-boronic acid pinacol ester → HCID 89445414, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluoropyridine-5-boronic acid pinacol ester | HCID 12177222 | — |
| Reactant | 5-(4-Fluoro-phenyl)-6-{4-[4-(4-fluoro-3-trifluoromethyl-phenyl)-1-methyl-1H-imidazol-2-yl]-piperidin-1-yl}-pyrimidin-4-ylamine | HCID 89442482 | — |
| Product | HCID 89445414 | HCID 89445414 | — |
Reaction Steps
The title compound was prepared in an analogous manner as 5-(4-Fluoro-phenyl)-6-{4-[4-(4-fluoro-3-trifluoromethyl-phenyl)-1-methyl-1H-imidazol-2-yl]-piperidin-1-yl}-pyrimidin-4-ylamine using (6-fluoropyridin-3-yl)boronic acid pinacol ester instead of 4-fluorophenylboronic acid. LC-MS: (M+1=516, obsd.=516).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09145392B2 |
| Source dataset | uspto-grants-2015_09 |
| ORD ID | ord-ab7bf9d341cc46368879b0f13b09ee38 |
| Source note | uspto-grants-2015_09 |