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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2283977Generated: November 1, 2026

(4-(Aminomethyl)phenyl)boronic acid → HCID 89442687, compound

https://huagongshe.com/reaction/2283977

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-(Aminomethyl)phenyl)boronic acidHCID 2734312—
Reactant5-(4-Fluoro-phenyl)-6-{4-[4-(4-fluoro-3-trifluoromethyl-phenyl)-1-methyl-1H-imidazol-2-yl]-piperidin-1-yl}-pyrimidin-4-ylamineHCID 89442482—
ProductHCID 89442687HCID 89442687—

Reaction Steps

The title compound was prepared in an analogous manner as 5-(4-Fluoro-phenyl)-6-{4-[4-(4-fluoro-3-trifluoromethyl-phenyl)-1-methyl-1H-imidazol-2-yl]-piperidin-1-yl}-pyrimidin-4-ylamine using (4-(aminomethyl)phenyl)boronic acid instead of 4-fluorophenylboronic acid. LC-MS: (M+1=526, obsd.=526).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09145392B2
Source datasetuspto-grants-2015_09
ORD IDord-e613b5bbac1c4ea0ba3f013651088e17
Source noteuspto-grants-2015_09