5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole → HCID 89445431, compound

Participants

Role	Name	HCID	Charge
Reactant	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole	HCID 2734772	—
Reactant	5-(4-Fluoro-phenyl)-6-{4-[4-(4-fluoro-3-trifluoromethyl-phenyl)-1-methyl-1H-imidazol-2-yl]-piperidin-1-yl}-pyrimidin-4-ylamine	HCID 89442482	—
Product	HCID 89445431	HCID 89445431	—

Reaction Steps

The title compound was prepared in an analogous manner as 5-(4-Fluoro-phenyl)-6-{4-[4-(4-fluoro-3-trifluoromethyl-phenyl)-1-methyl-1H-imidazol-2-yl]-piperidin-1-yl}-pyrimidin-4-ylamine using (1H-indol-5-yl)boronic acid pinacol ester instead of 4-fluorophenylboronic acid. LC-MS: (M+1=536, obsd.=536).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09145392B2
Source dataset	uspto-grants-2015_09
ORD ID	ord-e06fc9940d934d61a89e910c9ee14f07
Source note	uspto-grants-2015_09