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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2284085Generated: October 30, 2026

2-Butanamine, 2-methyl- → HCID 89442795, compound

https://huagongshe.com/reaction/2284085

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Butanamine, 2-methyl-HCID 68986—
Reactant4-Amino-6-{4-[1-[2-(cyclopropylmethyl-amino)-ethyl]-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-piperidin-1-yl}-pyrimidine-5-carbonitrileHCID 89442547—
ProductHCID 89442795HCID 89442795—

Reaction Steps

The title compound was prepared in an analogous manner as 4-Amino-6-{4-[1-[2-(cyclopropylmethyl-amino)-ethyl]-4-(4-fluoro-3-trifluoromethyl-phenyl)-1H-imidazol-2-yl]-piperidin-1-yl}-pyrimidine-5-carbonitrile using tert-amylamine instead of cyclopropylmethylamine. LC-MS: (M+1=545, obsd.=545).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09145392B2
Source datasetuspto-grants-2015_09
ORD IDord-eb81ef110f2f4b70afb872758eab3b00
Source noteuspto-grants-2015_09