N-cyclopropyl-4-formylbenzamide → HCID 178521800, compound

HRID 2284140Notes

Reaction equation

HRID 2284140 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([NH:13][C:14](=[O:26])[C:15]2[CH:20]=[CH:19][C:18]([N:21]3[CH2:25][CH2:24][CH2:23][CH2:22]3)=[CH:17][CH:16]=2)[CH:7]=[CH:8][C:9]=1[N+:10]([O-])=O)([O-])=O.[CH:27]1([NH:30][C:31]([C:33]2[CH:40]=[CH:39][C:36]([CH:37]=O)=[CH:35][CH:34]=2)=[O:32])[CH2:29][CH2:28]1>>[CH:27]1([NH:30][C:31](=[O:32])[C:33]2[CH:40]=[CH:39][C:36]([C:37]3[NH:10][C:9]4[CH:8]=[CH:7][C:6]([NH:13][C:14](=[O:26])[C:15]5[CH:20]=[CH:19][C:18]([N:21]6[CH2:25][CH2:24][CH2:23][CH2:22]6)=[CH:17][CH:16]=5)=[CH:5][C:4]=4[N:1]=3)=[CH:35][CH:34]=2)[CH2:28][CH2:29]1

Participants

3

Reactant 2

HCID 28818865N-cyclopropyl-4-formylbenzamideHCID 86673966N-(3,4-dinitrophenyl)-4-pyrrolidinylbenzamide

Product 1

HCID 178521800HCID 178521800, compound

Procedure

Compound 228 was prepared according to the procedure similar to that described in Scheme III from N-(3,4-dinitrophenyl)-4-pyrrolidinylbenzamide and 4-cyclopropylaminocarbonylbenzaldehyde. [M+H]+ calcd for C28H27N5O2: 466.23; found: 466.55.

Sources & evidence

ORD record
ord-171fb022f3404f619630f701e61fa718
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

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