Benzaldehyde, 4-(2-hydroxyethoxy)- → HCID 178521816, compound

HRID 2284150Notes

Reaction equation

HRID 2284150 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([NH:13][C:14]([C:16]2[CH:17]=[N:18][C:19]([N:22]3[CH2:26][CH2:25][CH2:24][CH2:23]3)=[N:20][CH:21]=2)=[O:15])[CH:7]=[CH:8][C:9]=1[N+:10]([O-])=O)([O-])=O.[OH:27][CH2:28][CH2:29][O:30][C:31]1[CH:38]=[CH:37][C:34]([CH:35]=O)=[CH:33][CH:32]=1>>[OH:27][CH2:28][CH2:29][O:30][C:31]1[CH:38]=[CH:37][C:34]([C:35]2[NH:10][C:9]3[CH:8]=[CH:7][C:6]([NH:13][C:14]([C:16]4[CH:17]=[N:18][C:19]([N:22]5[CH2:26][CH2:25][CH2:24][CH2:23]5)=[N:20][CH:21]=4)=[O:15])=[CH:5][C:4]=3[N:1]=2)=[CH:33][CH:32]=1

Participants

3

Reactant 2

HCID 89178Benzaldehyde, 4-(2-hydroxyethoxy)-HCID 86673969N-(3,4-dinitrophenyl)-2-(pyrrolidin-1-yl)pyrimidine-5-carboxamide

Product 1

HCID 178521816HCID 178521816, compound

Procedure

Compound 243 was prepared according to the procedure similar to that described in Scheme III from N-(3,4-dinitrophenyl)-2-(pyrrolidin-1-yl)pyrimidine-5-carboxamide and 4-(2-hydroxyethoxy)benzaldehyde. [M+H]+ calcd for C24H24N6O3: 445.20; found: 444.87.

Sources & evidence

ORD record
ord-6173e3ed149044ce8a4ecfb5cd7671e5
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

Loading…