HCID 67112380, compound → HCID 178521815, compound

HRID 2284174Notes

Reaction equation

[OH:1][CH2:2][CH2:3][N:4]([CH2:21][CH2:22][OH:23])[C:5]1[CH:10]=[CH:9][C:8]([C:11]2[NH:12][C:13]3[CH:19]=[C:18]([NH2:20])[CH:17]=[CH:16][C:14]=3[N:15]=2)=[CH:7][CH:6]=1.[OH:24][CH2:25][CH2:26][N:27]([CH2:46][CH2:47][OH:48])[C:28]1[CH:33]=[CH:32][C:31]([C:34]2[NH:35][C:36]3[CH:42]=[C:41]([C:43]([O-])=[O:44])[CH:40]=[CH:39][C:37]=3[N:38]=2)=[CH:30][CH:29]=1>>[OH:24][CH2:25][CH2:26][N:27]([CH2:46][CH2:47][OH:48])[C:28]1[CH:33]=[CH:32][C:31]([C:34]2[NH:35][C:36]3[CH:42]=[C:41]([C:43]([NH:20][C:18]4[CH:17]=[CH:16][C:14]5[NH:15][C:11]([C:8]6[CH:9]=[CH:10][C:5]([N:4]([CH2:21][CH2:22][OH:23])[CH2:3][CH2:2][OH:1])=[CH:6][CH:7]=6)=[N:12][C:13]=5[CH:19]=4)=[O:44])[CH:40]=[CH:39][C:37]=3[N:38]=2)=[CH:30][CH:29]=1

Participants

Reactant 2

HCID 67112380HCID 67112380, compound

HCID 86673978HCID 86673978, compound

Product 1

HCID 178521815HCID 178521815, compound

Procedure

Compound 289 was prepared according to the procedure similar to that described in Scheme V from 2-(4-(bis(2-hydroxyethyl)amino)phenyl)-5-aminobenzimidazole and 2-(4-(bis(2-hydroxyethyl)amino)phenyl)benzimidazole-5-carboxylate. [M+H]+ calcd for C35H37N7O5: 636.29; found: 636.06.

Sources & evidence

ORD record: ord-a4209847299044b597d2c6c577fd589e
Source dataset: uspto-grants-2015_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09144557B2

Reaction notes

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