5-Aminobenzimidazole → HCID 178509622, compound

HRID 2284177Notes

Reaction equation

[NH2:1][C:2]1[CH:10]=[CH:9][C:5]2[N:6]=[CH:7][NH:8][C:4]=2[CH:3]=1.[C:11]([C:13]1[CH:18]=[CH:17][C:16]([C:19]2[NH:20][C:21]3[CH:27]=[C:26]([C:28]([O-:30])=O)[CH:25]=[CH:24][C:22]=3[N:23]=2)=[CH:15][CH:14]=1)#[N:12]>>[C:11]([C:13]1[CH:14]=[CH:15][C:16]([C:19]2[NH:20][C:21]3[CH:27]=[C:26]([C:28]([NH:1][C:2]4[CH:10]=[CH:9][C:5]5[NH:6][C:7]([C:16]6[CH:17]=[CH:18][C:13]([C:11]#[N:12])=[CH:14][CH:15]=6)=[N:8][C:4]=5[CH:3]=4)=[O:30])[CH:25]=[CH:24][C:22]=3[N:23]=2)=[CH:17][CH:18]=1)#[N:12]

Participants

Reactant 2

HCID 136235-Aminobenzimidazole

HCID 86673979HCID 86673979, compound

Product 1

HCID 178509622HCID 178509622, compound

Procedure

Compound 295 was prepared according to the procedure similar to that described in Scheme V from 2-(4-cyano)phenyl)-5-aminobenzimidazole and 2-(4-cyanophenyl)benzimidazole-5-carboxylate. [M+H]+ calcd for C29H17N7O: 480.15; found: 479.89.

Sources & evidence

ORD record: ord-0ef0610c0dc64e82936e632a47b889be
Source dataset: uspto-grants-2015_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09144557B2

Reaction notes

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