5-Aminobenzimidazole → HCID 178509623, compound

HRID 2284179Notes

Reaction equation

[NH2:1][C:2]1[CH:10]=[CH:9][C:5]2[N:6]=[CH:7][NH:8][C:4]=2[CH:3]=1.[O:11]1[CH2:16][CH2:15][N:14]([C:17]2[CH:22]=[CH:21][C:20]([C:23]3[NH:24][C:25]4[CH:31]=[C:30]([C:32]([O-:34])=O)[CH:29]=[CH:28][C:26]=4[N:27]=3)=[CH:19][CH:18]=2)[CH2:13][CH2:12]1>>[C:23]([C:20]1[CH:21]=[CH:22][C:17]([C:7]2[NH:6][C:5]3[CH:9]=[CH:10][C:2]([NH:1][C:32]([C:30]4[CH:29]=[CH:28][C:26]5[N:27]=[C:23]([C:20]6[CH:19]=[CH:18][C:17]([N:14]7[CH2:15][CH2:16][O:11][CH2:12][CH2:13]7)=[CH:22][CH:21]=6)[NH:24][C:25]=5[CH:31]=4)=[O:34])=[CH:3][C:4]=3[N:8]=2)=[CH:18][CH:19]=1)#[N:24]

Participants

Reactant 2

HCID 136235-Aminobenzimidazole

HCID 86673980HCID 86673980, compound

Product 1

HCID 178509623HCID 178509623, compound

Procedure

Compound 298 was prepared according to the procedure similar to that described in Scheme V from 2-(4-cyano)phenyl)-5-aminobenzimidazole and 2-(4-morpholinophenyl)benzimidazole-5-carboxylate. [M+H]+ calcd for C32H25N7O2: 540.21; found: 539.97.

Sources & evidence

ORD record: ord-ade8694aacde4eea9e2be044bf5e1195
Source dataset: uspto-grants-2015_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09144557B2

Reaction notes

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