HCID 17325486, compound → HCID 178521807, compound

HRID 2284180Notes

Reaction equation

HRID 2284180 reaction equation
[O:1]1[CH2:6][CH2:5][N:4]([C:7]2[CH:12]=[CH:11][C:10]([C:13]3[NH:14][C:15]4[CH:21]=[C:20]([NH2:22])[CH:19]=[CH:18][C:16]=4[N:17]=3)=[CH:9][CH:8]=2)[CH2:3][CH2:2]1.[OH:23][CH2:24][CH2:25][O:26][C:27]1[CH:32]=[CH:31][C:30]([C:33]2[NH:34][C:35]3[CH:41]=[C:40]([C:42]([O-])=[O:43])[CH:39]=[CH:38][C:36]=3[N:37]=2)=[CH:29][CH:28]=1>>[OH:23][CH2:24][CH2:25][O:26][C:27]1[CH:28]=[CH:29][C:30]([C:33]2[NH:34][C:35]3[CH:41]=[C:40]([C:42]([NH:22][C:20]4[CH:19]=[CH:18][C:16]5[NH:17][C:13]([C:10]6[CH:11]=[CH:12][C:7]([N:4]7[CH2:5][CH2:6][O:1][CH2:2][CH2:3]7)=[CH:8][CH:9]=6)=[N:14][C:15]=5[CH:21]=4)=[O:43])[CH:39]=[CH:38][C:36]=3[N:37]=2)=[CH:31][CH:32]=1

Participants

3

Reactant 2

HCID 17325486HCID 17325486, compoundHCID 52397464HCID 52397464, compound

Product 1

HCID 178521807HCID 178521807, compound

Procedure

Compound 299 was prepared according to the procedure similar to that described in Scheme V from 2-(4-morpholinophenyl)-5-aminobenzimidazole and 2-(4-(2-hydroxyethoxy)phenyl)benzimidazole-5-carboxylate. [M+H]+ calcd for C33H30N6O4: 575.23; found: 575.07.

Sources & evidence

ORD record
ord-7ad171b416894ea09aa58896fcc9795b
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

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