4,4'-Diaminobenzophenone → N,N'-(carbonylbis(4,1-phenylene))bis(4-(4-methylpiperazin-1-yl)benzamide)

HRID 2284182Notes

Reaction equation

HRID 2284182 reaction equation
[NH2:1][C:2]1[CH:16]=[CH:15][C:5]([C:6]([C:8]2[CH:13]=[CH:12][C:11]([NH2:14])=[CH:10][CH:9]=2)=[O:7])=[CH:4][CH:3]=1.[CH3:17][N:18]1[CH2:23][CH2:22][N:21]([C:24]2[CH:32]=[CH:31][C:27]([C:28]([O-])=[O:29])=[CH:26][CH:25]=2)[CH2:20][CH2:19]1>>[C:6]([C:8]1[CH:13]=[CH:12][C:11]([NH:14][C:28](=[O:29])[C:27]2[CH:31]=[CH:32][C:24]([N:21]3[CH2:22][CH2:23][N:18]([CH3:17])[CH2:19][CH2:20]3)=[CH:25][CH:26]=2)=[CH:10][CH:9]=1)([C:5]1[CH:15]=[CH:16][C:2]([NH:1][C:28](=[O:29])[C:27]2[CH:26]=[CH:25][C:24]([N:21]3[CH2:20][CH2:19][N:18]([CH3:17])[CH2:23][CH2:22]3)=[CH:32][CH:31]=2)=[CH:3][CH:4]=1)=[O:7]

Participants

3

Reactant 2

HCID 691494,4'-DiaminobenzophenoneHCID 866739814-(4-Methylpiperazino)benzoate

Product 1

HCID 67112786N,N'-(carbonylbis(4,1-phenylene))bis(4-(4-methylpiperazin-1-yl)benzamide)

Procedure

Compound 316 was prepared according to the procedure described in Scheme IV from 4,4′-diaminobenzophenone and 4-(4-methylpiperazino)benzoate. [M+H]+ calcd for C37H41N6O3: 617.32; found: 617.12.

Sources & evidence

ORD record
ord-dfbffd664465455b98db86ee3183f399
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

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