4,4'-Diaminobenzophenone → N,N'-(carbonylbis(4,1-phenylene))bis(4-(piperazin-1-yl)benzamide)

HRID 2284183Notes

Reaction equation

[NH2:1][C:2]1[CH:16]=[CH:15][C:5]([C:6]([C:8]2[CH:13]=[CH:12][C:11]([NH2:14])=[CH:10][CH:9]=2)=[O:7])=[CH:4][CH:3]=1.[N:17]1([C:23]2[CH:31]=[CH:30][C:26]([C:27]([O-])=[O:28])=[CH:25][CH:24]=2)[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]1>>[C:6]([C:8]1[CH:13]=[CH:12][C:11]([NH:14][C:27](=[O:28])[C:26]2[CH:30]=[CH:31][C:23]([N:17]3[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]3)=[CH:24][CH:25]=2)=[CH:10][CH:9]=1)([C:5]1[CH:15]=[CH:16][C:2]([NH:1][C:27](=[O:28])[C:26]2[CH:25]=[CH:24][C:23]([N:17]3[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]3)=[CH:31][CH:30]=2)=[CH:3][CH:4]=1)=[O:7]

Participants

Reactant 2

HCID 691494,4'-Diaminobenzophenone

HCID 166413374-Piperazinobenzoate

Product 1

HCID 67112391N,N'-(carbonylbis(4,1-phenylene))bis(4-(piperazin-1-yl)benzamide)

Procedure

Compound 317 was prepared according to the procedure described in Scheme IV from 4,4′-diaminobenzophenone and 4-piperazinobenzoate. [M+H]+ calcd for C35H37N6O3: 589.29; found: 589.07.

Sources & evidence

ORD record: ord-959dbd720e914c3a9ea8c6aef4b354c5
Source dataset: uspto-grants-2015_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09144557B2

Reaction notes

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