4-Dimethylaminobenzoate → N-(1-(4-(4-Dimethylaminobenzamido)phenyl)-1H-indol-5-yl)-4-dimethylaminobenzamide

HRID 2284193Notes

Reaction equation

HRID 2284193 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([C:11]1[CH:16]=[CH:15][C:14]([NH2:17])=[CH:13][CH:12]=1)[CH:6]=[CH:5]2.[CH3:18][N:19]([CH3:29])[C:20]1[CH:28]=[CH:27][C:23]([C:24]([O-])=[O:25])=[CH:22][CH:21]=1>>[CH3:18][N:19]([CH3:29])[C:20]1[CH:28]=[CH:27][C:23]([C:24]([NH:17][C:14]2[CH:15]=[CH:16][C:11]([N:7]3[C:8]4[C:4](=[CH:3][C:2]([NH:1][C:24](=[O:25])[C:23]5[CH:27]=[CH:28][C:20]([N:19]([CH3:29])[CH3:18])=[CH:21][CH:22]=5)=[CH:10][CH:9]=4)[CH:5]=[CH:6]3)=[CH:12][CH:13]=2)=[O:25])=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 69502454-DimethylaminobenzoateHCID 666357505-Amino-1-(4-aminophenyl)indole

Product 1

HCID 67113074N-(1-(4-(4-Dimethylaminobenzamido)phenyl)-1H-indol-5-yl)-4-dimethylaminobenzamide

Procedure

Compound 370 was prepared according to the procedure described in Scheme IV from 5-amino-1-(4-aminophenyl)indole and 4-dimethylaminobenzoate. [M+H]+ calcd for C32H31N5O2: 518.25; found: 517.95.

Sources & evidence

ORD record
ord-a725404db0dd409fbc9de647951c9580
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

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