4-Dimethylaminobenzoate → 4-(dimethylamino)-N-(1-(4-morpholinophenyl)-1H-indol-5-yl)benzamide

HRID 2284198Notes

Reaction equation

HRID 2284198 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([C:11]1[CH:16]=[CH:15][C:14]([N:17]3[CH2:22][CH2:21][O:20][CH2:19][CH2:18]3)=[CH:13][CH:12]=1)[CH:6]=[CH:5]2.[CH3:23][N:24]([CH3:34])[C:25]1[CH:33]=[CH:32][C:28]([C:29]([O-])=[O:30])=[CH:27][CH:26]=1>>[CH3:23][N:24]([CH3:34])[C:25]1[CH:33]=[CH:32][C:28]([C:29]([NH:1][C:2]2[CH:3]=[C:4]3[C:8](=[CH:9][CH:10]=2)[N:7]([C:11]2[CH:12]=[CH:13][C:14]([N:17]4[CH2:22][CH2:21][O:20][CH2:19][CH2:18]4)=[CH:15][CH:16]=2)[CH:6]=[CH:5]3)=[O:30])=[CH:27][CH:26]=1

Participants

3

Reactant 2

HCID 69502454-DimethylaminobenzoateHCID 866739865-Amino-1-(4-morpholinophenyl)indole

Product 1

HCID 671134904-(dimethylamino)-N-(1-(4-morpholinophenyl)-1H-indol-5-yl)benzamide

Procedure

Compound 376 was prepared according to the procedure described in Scheme IV from 5-amino-1-(4-morpholinophenyl)indole and 4-dimethylaminobenzoate. [M+H]+ calcd for C27H28N4O2: 441.22; found: 441.02.

Sources & evidence

ORD record
ord-deaecfc131a742e6ba38f42042bcf268
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

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