4-Morpholinobenzoate → N-(1-(4-Aminophenyl)-1H-indazol-5-yl)-4-morpholinobenzamide

HRID 2284199Notes

Reaction equation

HRID 2284199 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([C:11]1[CH:16]=[CH:15][C:14]([NH2:17])=[CH:13][CH:12]=1)[N:6]=[CH:5]2.[O:18]1[CH2:23][CH2:22][N:21]([C:24]2[CH:32]=[CH:31][C:27]([C:28]([O-])=[O:29])=[CH:26][CH:25]=2)[CH2:20][CH2:19]1>>[NH2:17][C:14]1[CH:15]=[CH:16][C:11]([N:7]2[C:8]3[C:4](=[CH:3][C:2]([NH:1][C:28](=[O:29])[C:27]4[CH:26]=[CH:25][C:24]([N:21]5[CH2:22][CH2:23][O:18][CH2:19][CH2:20]5)=[CH:32][CH:31]=4)=[CH:10][CH:9]=3)[CH:5]=[N:6]2)=[CH:12][CH:13]=1

Participants

3

Reactant 2

HCID 51582824-MorpholinobenzoateHCID 834142075-Amino-1-(4-aminophenyl)indazole

Product 1

HCID 67112841N-(1-(4-Aminophenyl)-1H-indazol-5-yl)-4-morpholinobenzamide

Procedure

Compound 381 was prepared according to the procedure described in Scheme IV from 5-amino-1-(4-aminophenyl)indazole and 4-morpholinobenzoate. [M+H]+ calcd for C24H23N5O2: 414.19; found: 414.01.

Sources & evidence

ORD record
ord-2fdb21d62ab642a989a21e99d4b992d2
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

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