4-Morpholinobenzoate → N-(1-(4-Cyanophenyl)-1H-indazol-5-yl)-4-morpholinobenzamide

HRID 2284205Notes

Reaction equation

HRID 2284205 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([C:11]1[CH:16]=[CH:15][C:14]([C:17]#[N:18])=[CH:13][CH:12]=1)[N:6]=[CH:5]2.[O:19]1[CH2:24][CH2:23][N:22]([C:25]2[CH:33]=[CH:32][C:28]([C:29]([O-])=[O:30])=[CH:27][CH:26]=2)[CH2:21][CH2:20]1>>[C:17]([C:14]1[CH:15]=[CH:16][C:11]([N:7]2[C:8]3[C:4](=[CH:3][C:2]([NH:1][C:29](=[O:30])[C:28]4[CH:27]=[CH:26][C:25]([N:22]5[CH2:23][CH2:24][O:19][CH2:20][CH2:21]5)=[CH:33][CH:32]=4)=[CH:10][CH:9]=3)[CH:5]=[N:6]2)=[CH:12][CH:13]=1)#[N:18]

Participants

3

Reactant 2

HCID 51582824-MorpholinobenzoateHCID 834142885-Amino-1-(4-cyanophenyl)indazole

Product 1

HCID 67113106N-(1-(4-Cyanophenyl)-1H-indazol-5-yl)-4-morpholinobenzamide

Procedure

Compound 405 was prepared according to the procedure described in Scheme IV from 5-amino-1-(4-cyanophenyl)indazole and 4-morpholinobenzoate. [M+H]+ calcd for C25H21N5O2: 424.17; found: 424.09.

Sources & evidence

ORD record
ord-175a1a95c5d547af8c2d803e1bad172b
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

Loading…