4-Morpholinobenzoate → HCID 178521804, compound

HRID 2284225Notes

Reaction equation

HRID 2284225 reaction equation
[O:1]1[CH2:6][CH2:5][N:4]([C:7]2[CH:15]=[CH:14][C:10]([C:11]([O-:13])=O)=[CH:9][CH:8]=2)[CH2:3][CH2:2]1.[NH2:16][C:17]1[CH:45]=[CH:44][C:20]2[N:21]=[C:22]([C:24]3[CH:29]=[CH:28][C:27]([N:30]4[CH2:35][CH2:34][CH:33]([CH2:36][CH2:37][N:38]5[CH2:43][CH2:42][O:41][CH2:40][CH2:39]5)[CH2:32][CH2:31]4)=[CH:26][CH:25]=3)[NH:23][C:19]=2[CH:18]=1>>[O:41]1[CH2:42][CH2:43][N:38]([CH2:37][CH2:36][CH:33]2[CH2:32][CH2:31][N:30]([C:27]3[CH:26]=[CH:25][C:24]([C:22]4[NH:21][C:20]5[CH:44]=[CH:45][C:17]([NH:16][C:11](=[O:13])[C:10]6[CH:9]=[CH:8][C:7]([N:4]7[CH2:3][CH2:2][O:1][CH2:6][CH2:5]7)=[CH:15][CH:14]=6)=[CH:18][C:19]=5[N:23]=4)=[CH:29][CH:28]=3)[CH2:35][CH2:34]2)[CH2:39][CH2:40]1

Participants

3

Reactant 2

HCID 51582824-MorpholinobenzoateHCID 671125645-Amino-2-(4-(4-(2-morpholinoethyl)piperidino)phenyl)benzimidazole

Product 1

HCID 178521804HCID 178521804, compound

Procedure

Compound 446 was prepared from 4-morpholinobenzoate and 5-amino-2-(4-(4-(2-morpholinoethyl)piperidino)phenyl)benzimidazole by standard conditions. [M+H]+ calcd for: C35H42N6O3; 595.33 found: 595.12.

Sources & evidence

ORD record
ord-2c07328ac77d43c09207c0de3535fb1e
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

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