Glycine → N-(2-(4-Morpholinophenyl)amino-2-oxoethyl)-4-dimethylaminobenzamide

Participants

Role	Name	HCID	Charge
Reactant	Glycine	HCID 750	—
Reactant	Benzenamine, 4-(4-morpholinyl)-	HCID 75655	—
Reactant	4-Dimethylaminobenzoate	HCID 6950245	—
Product	N-(2-(4-Morpholinophenyl)amino-2-oxoethyl)-4-dimethylaminobenzamide	HCID 67113647	—

Reaction Steps

Compound 467 was prepared according to the procedure described in Scheme IV from 4-morpholinoaniline, glycine, and 4-dimethylaminobenzoate. 1H NMR (500 MHz, CDCl3) δ 8.46 (s, 1H), 7.74 (s, J=9 Hz, 2H), 6.82 (t, J=5.5 Hz, 1H), 6.68 (d, J=9 Hz, 2H), 4.25 (d, J=5.5 Hz, 2H), 3.85 (m, 4H), 3.11 (m, 4H), 3.04 (s, 6H).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US09144557B2
Source dataset	uspto-grants-2015_09
ORD ID	ord-a7411be3a9ce44be9d9d2de48de4c08a
Source note	uspto-grants-2015_09