1H-Indole-5-Carboxylic Acid → HCID 67113724, compound
Reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([C:11]1[CH:16]=[CH:15][C:14]([NH2:17])=[CH:13][CH:12]=1)[N:6]=[CH:5]2.[NH:18]1[C:26]2[C:21](=[CH:22][C:23]([C:27]([OH:29])=O)=[CH:24][CH:25]=2)[CH:20]=[CH:19]1>>[NH:18]1[C:26]2[C:21](=[CH:22][C:23]([C:27]([NH:1][C:2]3[CH:3]=[C:4]4[C:8](=[CH:9][CH:10]=3)[N:7]([C:11]3[CH:16]=[CH:15][C:14]([NH:17][C:27]([C:23]5[CH:22]=[C:21]6[C:26](=[CH:25][CH:24]=5)[NH:18][CH:19]=[CH:20]6)=[O:29])=[CH:13][CH:12]=3)[N:6]=[CH:5]4)=[O:29])=[CH:24][CH:25]=2)[CH:20]=[CH:19]1Participants
3
Procedure
Compound 527 was prepared according to the procedure described in Scheme IV from 5-amino-1-(4-aminophenyl)indazole and 1H-indole-5-carboxylic acid. [M+H]+ calcd for C31H22N6O2: 511.18; found: 511.03.
Sources & evidence
- ORD record
- ord-5cf3a3901155466485acfc2f76f15e8e
- Source dataset
- uspto-grants-2015_09
- Patent number
- US09144557B2
Reaction notes
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