4-Morpholinobenzoate → 4-Morpholino-N-(2-(4-morpholinophenyl)-2H-indazol-5-yl)benzamide

HRID 2284256Notes

Reaction equation

HRID 2284256 reaction equation
[NH2:1][C:2]1[CH:10]=[CH:9][C:8]2[C:4](=[CH:5][N:6]([C:11]3[CH:16]=[CH:15][C:14]([NH2:17])=[CH:13][CH:12]=3)[N:7]=2)[CH:3]=1.[O:18]1[CH2:23][CH2:22][N:21]([C:24]2[CH:32]=[CH:31][C:27]([C:28]([O-:30])=O)=[CH:26][CH:25]=2)[CH2:20][CH2:19]1>>[O:18]1[CH2:19][CH2:20][N:21]([C:24]2[CH:25]=[CH:26][C:27]([C:28]([NH:1][C:2]3[CH:10]=[CH:9][C:8]4[C:4](=[CH:5][N:6]([C:11]5[CH:16]=[CH:15][C:14]([N:17]6[CH2:22][CH2:23][O:18][CH2:19][CH2:20]6)=[CH:13][CH:12]=5)[N:7]=4)[CH:3]=3)=[O:30])=[CH:31][CH:32]=2)[CH2:22][CH2:23]1

Participants

3

Reactant 2

HCID 51582824-MorpholinobenzoateHCID 671125805-Amino-2-(4-aminophenyl)indazole

Product 1

HCID 671136344-Morpholino-N-(2-(4-morpholinophenyl)-2H-indazol-5-yl)benzamide

Procedure

Compound 538 was prepared according to the procedure described in Scheme IV from 5-amino-2-(4-aminophenyl)indazole and 4-morpholinobenzoate. [M+H]+ calcd for C28H29N5O3: 484.23; found: 484.13.

Sources & evidence

ORD record
ord-cfe16afb98b04e1db55948a11bee2531
Source dataset
uspto-grants-2015_09
Patent number
US09144557B2

Reaction notes

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